About the Workshop
In this workshop, learn how 3D genomics provides access to sequence, structure, and regulatory landscapes of genomes in ways inaccessible via other technologies.
Topics:
- Histone H1 deficiency leads to aggressive B-cell lymphomas by disrupting 3D chromatin architecture | Ceyda Durmaz, Weill Cornell Medical College
- Highly contiguous Solanum genomes provide insight into the genetic basis of trait evolution | James Satterlee, Cold Springs Harbor Laboratory
Meet the Speakers
Ceyda Durmaz
Weill Cornell Medical CollegeCeyda will share her research using HiC, and other genome-wide approaches in mice modeling B-Cell lymphoma to systematically characterize the spatio-temporal re-organization of compartments and promoter-anchored interactions at high-resolution and show how Histone H1 deficiency contributes to cell-fate specific chromatin accessibility changes that drive lymphoma malignancy.
James Satterlee
Cold Springs Harbor LaboratoryJack will share his ongoing work to assemble high-quality chromosome-scale genomes across the highly diverse genus Solanum to understand how genome evolution has contributed to CNVs, trait diversity, and the predictability of genome editing for crop improvement by leveraging the power of HiC, long read sequencing and optical mapping.