![HiC Kit_Arima Genomics_9](https://arimagenomics.com/wp-content/files/IMG_1971_1.jpg)
Generate Comprehensive Insights
Generate dependable results from FFPE tissue samples to detect both coding and non-coding structural variants in this hard-to-use sample type. Learn more about our structural genomics application.
![FFPE vs Frozom Heat Map and Correlation Plot_Arima Genomics Genome wide HiC_3D Genome Structure_Image](https://arimagenomics.com/wp-content/files/FFPE-vs-Frozom-Heat-Map-and-Correlation-Plot_Arima-Genomics.png)
FFPE Sample Results are Highly Correlated to Frozen Tissues. Matched frozen and FFPE tissue of K562 cell cultures were processed with the Arima-HiC+ and Arima-HiC+ FFPE kits, respectively. Libraries were generated following Arima protocols and sequenced using Illumina next generation sequencing (57M and 27M reads were generated, respectively). Representative data for Chromosome 2 at 500 Mb are shown in a. Hi-C contact heat map (500Mb resolution) and b. correlation plot of the normalized Hi-C counts per bin for frozen versus FFPE samples showing a high correlation (r=0.987).
Arima SV Detection Assay Workflow
An end-to-end solution to take you from sample to insights.
![](https://arimagenomics.com/wp-content/files/HiC-Prep-Step_Icon_Arima-Genomics.png)
Sample Prep
Arima-HiC+ / Arima-HiC+ FFPE Chemistry
Works with cells, liquid biopsy, fresh/frozen tissue and formalin-fixed, paraffin embedded (FFPE) tissue.
![](https://arimagenomics.com/wp-content/files/Library-Prep-Step_Icon_Arima-Genomics.png)
Library Prep
Arima Library Prep
![](https://arimagenomics.com/wp-content/files/Sequencing-Step_Icon_Arima-Genomics.png)
Sequencing
Next Generation Sequencing
2 x 150 paired-end reads
Tested on Illumina, Element and Singular NGS platforms.
![](https://arimagenomics.com/wp-content/files/Data-Analysis-Step_Icon_Arima-Genomics.png)
Data Analysis
Arima Bioinformatics Platform
Leverage the Arima SV QC and Deep Sequencing pipelines.
Compatible with 50–500 million PE reads / clusters. We recommend at least 100M reads.
Matija Snuderl, MD
Director of Molecular Pathology and Diagnostics, NYU Langone Medical CenterExplore Our Resources
Learn more about how you can use Arima HiC+ Kits and Workflows in your research: