Characterize regulatory differences between samples
Generate conformational profiles of specific regions
Identify novel biomarkers and therapeutic targets
Capture HiC data shown at the BCR locus in K562 cells at progressively higher resolutions with bin sizes of (A) 25 kb, (B) 5 kb, and (C) 500 bp. (D) Approximate number of raw read-pairs necessary to obtain either 25 kb, 5 kb, or 500 bp resolution.
Arima Custom Capture Workflow
Rapidly go from sample to discovery with our easy-to-use workflow.
Rapid 6-hour Protocol
Begin with as few as 80k cells, compatible with most sample types
Library Prep + Target Capture
Optimized for Arima Capture-HiC
High on-target rates and DNA yield with 1-hour hybridization
Illumina Next Generation Sequencing
100M reads recommended for <5kb resolution of contacts
Open and Optimized Bioinformatics Pipelines
Built using the open-source HiCUP and CHiCAGO tools
Changhoon KimChanghoon Kim, PhD, Chief Technology Officer, Macrogen, Inc.
Explore our resources
Learn more about how you can use Arima-HiC+ for Custom Capture in your research: