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Arima Genomics has a Fresh Look — Welcome to Our New Website!

Proven Performance

Achieve greater accuracy for chromatin loop detection, even at reduced sequencing depths

Flexible Design

Partner with Arima to optimize target capture probes using our multiple design tiers and strategies

Increase Efficiency

Save time and money by streamlining your workflow and sequencing efforts to regions of interest

The Benefits of Custom Capture HiC

The Arima-HiC+ Kit and Arima Capture-HiC workflow are designed to speed time to discovery for variant, region, or promoter capture.

Characterize regulatory differences between samples

Generate conformational profiles of specific regions

Identify novel biomarkers and therapeutic targets

Region Capture – Assemble a 3D Profile of Chromosome Loci

Arima Capture HiC lets you identify sub-kilobase features. With this increased resolution, you can precisely identify long-range chromatin contacts and topological landmarks. Learn more about our human health and epigenetics applications.

Arima-Custom-Cature-Illustration

Capture HiC data shown at the BCR locus in K562 cells at progressively higher resolutions with bin sizes of (A) 25 kb, (B) 5 kb, and (C) 500 bp. (D) Approximate number of raw read-pairs necessary to obtain either 25 kb, 5 kb, or 500 bp resolution.

Arima Custom Capture Workflow

Rapidly go from sample to discovery with our easy-to-use workflow.

Hi-C Prep

Rapid 6-hour Protocol

Begin with as few as 80k cells, compatible with most sample types

Library Prep + Target Capture

Optimized for Arima Capture-HiC

High on-target rates and DNA yield with 1-hour hybridization

Sequencing

Illumina Next Generation Sequencing

100M reads recommended for <5kb resolution of contacts

Data Analysis

Open and Optimized Bioinformatics Pipelines

Built using the open-source HiCUP and CHiCAGO tools

Changhoon Kim

Changhoon Kim, PhD, Chief Technology Officer, Macrogen, Inc.
“The ability of Arima-HiC kits to deliver greater insight with less sequencing cost will be critical in enabling more researchers to leverage Hi-C technology for understanding gene regulation within the three-dimensional context of the genome.”

Explore our resources

Learn more about how you can use Arima-HiC+ for Custom Capture in your research:

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