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Sex-specific multi-level 3D genome dynamics in the mouse brain

Devin Rocks, Mamta Shukla, Silvia C. Finnemann, Achyuth Kalluchi, M. Jordan Rowley, Marija Kundakovic..

Oncogenic 3D genome conformations identify novel therapeutic targets in ependymoma

Konstantin Okonechnikov, Aylin Camgoz, Donglim Esther Park, Owen Chapman, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Cha..

Altered 3D chromatin structure permits inversional recombination at the IgH locus

Xiang Qiu, Fei Ma, Mingming Zhao, Yaqiang Cao, Lillian Shipp, Angela Liu, Arun Dutta, Amit Singh, Fatima Zohra Braikia, Supriyo De, William H Wood 3rd, Kevin G Becker, Weiqiang Zhou, Hongkai Ji, Keji ..

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Testimonial Image
Testimonial Image

We are pleased with the informative nature and quality of the Arima-HiChIP data.  Not only do we observe intrachromosomal cis-regulatory interactions across cancer genomes, but also interchromosomal ectopic cis-regulatory interactions on rearranged chromosomes.  We think this data will help better delineate the relationship between genetic and epigenetic driver events in cancer.

Peter Scacheri, PhD

Professor, Case Western University School of Medicine

Arima Genomics is an integral technology partner of the G10K consortium and Phase I of the VGP project. Arima was selected for Phase I based on the quality of their data, proven by their ability to generate reproducible and high-quality data despite variability in input sample quality and quantity. 

Gene Myers, PhD

G10K Council Member and Director, Max-Planck Institute of Molecular Cell Biology and Genetics

When we tested Arima-HiC kit in our hands, we consistently got very high-quality libraries. Particularly, the fraction of interchromosomal reads is reduced.

Daan Noordermeer, PhD

Group Leader, Chromatin Dynamics Group at French National Centre for Scientific Research (CNRS)