Benefits of Arima-HiC+ for HiChIP
The HiC+ Kit and HiChiP workflow is ideal for a NGS-based assay for multi-omic analyses of chromatin protein binding and associated chromatin interactions to:
Target H3K27ac or H3K4me3 using validated antibodies specific for interactions linking active regulatory domains
Optimize for ChIP-enriched long-range interactions
Uncover cell-type specific chromatin loops associated with active promoters
Accurately Identify Loops with High Reproducibility
With reproducibility greater than 80%, you can confidently identify not only the ChIP enrichment of your target, but also 3D connectivity between acetylation sites. Learn more about our human health and epigenetics applications.
HiChIP connectivity between the MYC locus and distal H3K27 acetylation sites in human lymphocytes.
Arima Workflow
With our easy-to-use workflow you can rapidly go from sample to discovery.
Hi-C Prep
Rapid 6-hour Protocol
Compatible with cell lines, primary cells, fresh/frozen tissue and FFPE*
*Arima-HiC+ FFPE kit
Library Prep
Pre-validated Library Prep Protocol
Kapa Hyper Prep (standard input)
Swift Accel-NGS 2S (low input)
Sequencing
Illumina Next Generation Sequencing
Read depth dependent on antibody and desired level of resolution
Data Analysis
Open and Optimized Bioinformatics Pipeline
Arima-MAPS 2.0
Explore Our Resources
Learn more about how you can use Arima-HiC+ for HiChIP in your research:
