Hi-C is a proximity ligation method that captures the three-dimensional organizational structure of chromatin, where genomic sequences that are closer to each other in the 3D space can be distal to each other in linear distance – thereby preserving long range genetic sequence and structure information prior to sequencing. Post-sequencing, this data can be used for multiple genomic applications including identification of promoter-enhancer interactions for gene regulation studies and scaffolding contigs for genome assemblies to define chromosomes de novo.
The Arima-HiC Kit is highly simplified and robust protocol that streamlines Hi-C to a 6-hour workflow followed by library prep and next-generation sequencing. With its ease of use and proven performance, Arima-HiC empowers researchers to apply long-range genetic sequence and structure information towards the understanding of a wide range of biological processes—from human health and disease to species evolution.
Obtain the most accurate and reproducible results at reduced sequencing depth for greater efficiency of sequencing dollar.
Ascertain library quality to ensure sequencing success with quick and easy QC steps
Fast & User-Friendly Workflow
Expedite time to insight with a simple and rapid 6-hour Hi-C workflow
Flexible Input Requirements
Interrogate samples with limited available material with an optimized protocol for low sample input
Learn more about how the Arima-HiC kit can accelerate your time to biological insight in epigenetics and genome assembly applications.