How the 3D Genome Reveals Novel Disease Mechanisms and Therapeutic Targets

Current methods for sequencing FFPE tumor tissues often fail to identify genomic alterations such as gene fusions responsible for driving disease. In this workshop, recorded at the AMP 2022 meeting, learn how a 3D genomics-based approach consistently detected gene fusions and structural variants of clinical significance in driver-negative clinical samples, as well as archival FFPE tissue samples for which other technologies, such as RNA-seq, are unsuccessful.