About the Webinar
Our presentation will unveil groundbreaking, unpublished findings on how transposable elements reshape the 3D genome architecture to fuel resistance to CDK4/6 inhibitors in breast cancer—revealing new frontiers for therapeutic intervention.
What You Will Learn:
Discover how transposable elements are reactivated in drug-resistant breast cancer and their unexpected role as regulatory enhancers.
Explore the latest 3D genome mapping techniques (Hi-C, Capture Hi-C) and how they reveal novel chromatin interactions driving oncogenic gene expression.
Understand the therapeutic potential of targeting genome architecture and transposable elements to overcome resistance in ER+ breast cancer.
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Meet the Speakers
Joanna Achinger-Kawecka, PhD
Group Leader, SAiGENCIJoanna is Group Leader at SAiGENCI, University of Adelaide, where she founded the 3D Chromatin Organisation Laboratory to study how 3D genome folding and transposable elements influence gene expression in cancer, aiming to inform new therapies. Her pioneering work has advanced technologies for mapping chromatin structure and deepened understanding of cancer epigenomics.
Kristin Sikkink, PhD
Director of Research, Arima GenomicsKristin is our newly appointed Director of Research and holds a PhD in Biology. She leads and manages Arima's clinical and discovery research programs.