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About the Webinar

GWAS studies have identified a large number of single nucleotide polymorphisms that are associated with complex disease risk. The vast majority of these risk variants map to non-coding regions of the genome, and their functional interpretation remains challenging.

During this webinar, Dr. Orozco will share how functional genomics can help us understand what biological mechanisms are altered by disease associated-variants, with a focus on how 3D chromatin structure can be used to identify disease-causing genes in autoimmune disorders.

Key Takeaways:

  • Learn how 3D genomics provides access to sequence, structure, and regulatory landscapes of genomes in ways inaccessible via other technologies
  • Understand the utility of 3D genomics for understanding disease-associated variants in non-coding regions in autoimmune disorders.

Meet the Speakers

Gisela Orozco, PhD

Centre of Excellence in Genetics and Genomics Versus Arthritis, University of Manchester

Dr. Gisela Orozco is a Wellcome Senior Fellow in the Centre for Genetics and Genomics Versus Arthritis at the University of Manchester. Her main research interest is the genetics of complex diseases, with a focus on using functional genomics to understand how genetic variants affect genes and biological mechanisms that drive disease.

Kristin Sikkink, PhD

Scientist, Arima Genomics

Dr. Kristin Sikkink is a Senior Scientist in Scientific Affairs and holds a PhD in Biology. At Arima, she spearheads research and development initiatives.