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Breakfast Symposium

Hidden Regulators: How Transposable Elements Shape the 3D Genome in Resistant Breast Cancer

Wednesday, June 18, 2025 | 8:30 – 9:15 AM | Auditorium 6+7

Join our presentation unveiling groundbreaking, unpublished findings on how transposable elements reshape the 3D genome architecture to fuel resistance to CDK4/6 inhibitors in breast cancer—revealing new frontiers for therapeutic intervention. Breakfast, refreshments, and coffee will be served!

What you will learn:

  • Discover how transposable elements are reactivated in drug-resistant breast cancer and their unexpected role as regulatory enhancers.

  • Explore the latest 3D genome mapping techniques (Hi-C, Capture Hi-C) and how they reveal novel chromatin interactions driving oncogenic gene expression.

  • Understand the therapeutic potential of targeting genome architecture and transposable elements to overcome resistance in ER+ breast cancer.

 

Stop by Booth #36

Visit our Arima booth during the conference and connect with our team!

  • Meet the Team: Chat with our scientists about your projects and learn about the latest in 3D genomics.
  • Fun Swag: Take home some Arima goodies to remember the event.
  • Arima Kit Raffle: Enter for a chance to win an Arima kit!

Save Your Seat

Meet the Speakers

Joanna Achinger-Kawecka, PhD

Group Leader, SAiGENCI

Dr. Joanna Achinger-Kawecka is Group Leader at the South Australian immunoGENomics Cancer Institute (SAiGENCI), University of Adelaide. She earned her PhD in cancer epigenetics from the University of Tubingen, Germany, as a Marie Curie Fellow, and later joined the Garvan Institute in Sydney, where she established the 3D Epigenome in Cancer group. Her pioneering work has advanced our understanding of 3D genome and epigenome organization in cancer, including the development of new technologies for mapping chromatin structure. In 2024, she founded the 3D Chromatin Organisation Laboratory at SAiGENCI, focusing on how 3D genome folding and transposable elements regulate gene expression in cancer, with the aim of informing novel therapeutic strategies.

Anthony Schmitt, PhD

SVP of Science, Arima Genomics

Anthony Schmitt, PhD, is the SVP of Science at Arima Genomics, where his expertise in 3D genomics has been pivotal to the company's development of Hi-C technology and its applications in genomics research. He received his PhD from the University of California, San Diego, where he developed novel methodologies for understanding gene regulation using 3D genomics approaches. Since Arima’s inception, Anthony has led the development of the core Arima Hi-C chemistry and technology platform, as well as industry partnerships and academic collaborations.