About the Webinar
This webinar introduces Capture-C MPRA, a groundbreaking genomic technology that integrates 3D genome mapping with high-throughput functional assays to unravel the complex regulatory landscape of gene expression. Attendees will discover how this dual-purpose method links physical DNA interactions with regulatory activity, enabling precise mapping of enhancers and silencers to their target genes in a single experiment.
What You Will Learn:
- Discover how Capture-C MPRA combines promoter capture Hi-C and massively parallel reporter assays to simultaneously map promoter interactions and measure the regulatory activity of distal elements.
- Learn how this approach systematically identifies and assigns enhancers and silencers to specific genes, revealing new insights into enhancer-promoter specificity and the rules governing gene regulation.
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Meet the Speakers
Coline Arnould, PhD
UCSFColine Arnould is a molecular biologist with expertise in DNA damage repair, chromatin architecture, and gene regulation. During her Ph.D. with Dr. Gaëlle Legube in France, Coline uncovered a critical role for 3D genome organization in double-strand break repair and cancer. As a postdoctoral researcher in Dr. Nadav Ahituv’s lab at UCSF, she now leverages cutting-edge genomic tools to investigate gene regulatory elements within the context of chromatin architecture.
Andrew Kao
Arima GenomicsAndrew is a Technical Applications Scientist with a deep understanding of Arima HiC technology and a dedicated focus on supporting customers in advancing their research. Andrew leverages his expertise to provide technical guidance, troubleshoot experimental workflows, and ensure the successful implementation of Arima HiC technologies for researchers and industry partners. He attended the University of California, Riverside.