In this application brochure, learn about two exciting case studies:
- How 3D genomics helped identify a novel gene translocation in a pediatric patient with Stage 2 glioma.
- How Arima technology found gene fusions missed by DNA, RNA, and FISH in a patient presenting with IDH1/2 wild-type diffuse glioma.
Giorgio G. Galli, PhD
Group Leader, Oncology Drug Discovery Biology, Novartis Institutes for Biomedical Research“Hi-C is a powerful tool for conducting genome-wide analyses. We used Hi-C to narrow down the window of the scRNA-seq data and were able to successfully dissect a transcriptional regulatory network and identify the function of non-coding elements of cancer cells.”